How dormant cancer persists and reawakens

被引:56
作者
Aguirre-Ghiso, Julio A. [1 ,2 ]
机构
[1] Icahn Sch Med Mt Sinai, Black Family Stem Cell Inst, Dept Otolaryngol, Div Hematol & Oncol,Dept Med, New York, NY 10029 USA
[2] Icahn Sch Med Mt Sinai, Precis Immunol Inst, Dept Otolaryngol, Div Hematol & Oncol,Dept Med, New York, NY 10029 USA
关键词
TUMOR DORMANCY; CELLS; MECHANISMS;
D O I
10.1126/science.aav0191
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];
摘要
引用
收藏
页码:1314 / +
页数:2
相关论文
共 14 条
[1]
Quiescent Tissue Stem Cells Evade Immune Surveillance [J].
Agudo, Judith ;
Park, Eun Sook ;
Rose, Samuel A. ;
Alibo, Eziwoma ;
Sweeney, Robert ;
Dhainaut, Maxime ;
Kobayashi, Koichi S. ;
Sachidanandam, Ravi ;
Baccarini, Alessia ;
Merad, Miriam ;
Brown, Brian D. .
IMMUNITY, 2018, 48 (02) :271-+
[2]
Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice [J].
Albrengues, Jean ;
Shields, Mario A. ;
Ng, David ;
Park, Chun Gwon ;
Ambrico, Alexandra ;
Poindexter, Morgan E. ;
Upadhyay, Priya ;
Uyeminami, Dale L. ;
Pommier, Arnaud ;
Kuttner, Victoria ;
Bruzas, Emilis ;
Maiorino, Laura ;
Bautista, Carmelita ;
Carmona, Ellese M. ;
Gimotty, Phyllis A. ;
Fearon, Douglas T. ;
Chang, Kenneth ;
Lyons, Scott K. ;
Pinkerton, Kent E. ;
Trotman, Lloyd C. ;
Goldberg, Michael S. ;
Yeh, Johannes T. -H. ;
Egeblad, Mikala .
SCIENCE, 2018, 361 (6409) :1353-+
[3]
Stem cell function and stress response are controlled by protein synthesis [J].
Blanco, Sandra ;
Bandiera, Roberto ;
Popis, Martyna ;
Hussain, Shobbir ;
Lombard, Patrick ;
Aleksic, Jelena ;
Sajini, Abdulrahim ;
Tanna, Hinal ;
Cortes-Garrido, Rosana ;
Gkatza, Nikoletta ;
Dietmann, Sabine ;
Frye, Michaela .
NATURE, 2016, 534 (7607) :335-+
[4]
Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1 [J].
El Rayes, Tina ;
Catena, Raul ;
Lee, Sharrell ;
Stawowczyk, Marcin ;
Joshi, Natasha ;
Fischbach, Claudia ;
Powell, Charles A. ;
Dannenberg, Andrew J. ;
Altorki, Nasser K. ;
Gao, Dingcheng ;
Mittal, Vivek .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (52) :16000-16005
[5]
The perivascular niche regulates breast tumour dormancy [J].
Ghajar, Cyrus M. ;
Peinado, Hector ;
Mori, Hidetoshi ;
Matei, Irina R. ;
Evason, Kimberley J. ;
Brazier, Helene ;
Almeida, Dena ;
Koller, Antonius ;
Hajjar, Katherine A. ;
Stainier, Didier Y. R. ;
Chen, Emily I. ;
Lyden, David ;
Bissell, Mina J. .
NATURE CELL BIOLOGY, 2013, 15 (07) :807-+
[6]
Mechanisms Governing Metastatic Dormancy and Reactivation [J].
Giancotti, Filippo G. .
CELL, 2013, 155 (04) :750-764
[7]
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth [J].
Hart, Lori S. ;
Cunningham, John T. ;
Datta, Tatini ;
Dey, Souvik ;
Tameire, Feven ;
Lehman, Stacey L. ;
Qiu, Bo ;
Zhang, Haiyan ;
Cerniglia, George ;
Bi, Meixia ;
Li, Yan ;
Gao, Yan ;
Liu, Huayi ;
Li, Changhong ;
Maity, Amit ;
Thomas-Tikhonenko, Andrei ;
Perl, Alexander E. ;
Koong, Albert ;
Fuchs, Serge Y. ;
Diehl, J. Alan ;
Mills, Ian G. ;
Ruggero, Davide ;
Koumenis, Constantinos .
JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (12) :4621-4634
[8]
The Unfolded Protein Response and Cell Fate Control [J].
Hetz, Claudio ;
Papa, Feroz R. .
MOLECULAR CELL, 2018, 69 (02) :169-181
[9]
Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases [J].
Pommier, Arnaud ;
Anaparthy, Naishitha ;
Memos, Nicoletta ;
Kelley, Z. Larkin ;
Gouronnec, Alizee ;
Yan, Ran ;
Auffray, Cedric ;
Albrengues, Jean ;
Egeblad, Mikala ;
Iacobuzio-Donahue, Christine A. ;
Lyons, Scott K. ;
Fearon, Douglas T. .
SCIENCE, 2018, 360 (6394) :1202-+
[10]
PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma [J].
Pytel, Dariusz ;
Gao, Yan ;
Mackiewicz, Katarzyna ;
Katlinskaya, Yuliya V. ;
Staschke, Kirk A. ;
Paredes, Maria C. G. ;
Yoshida, Akihiro ;
Qie, Shuo ;
Zhang, Gao ;
Chajewski, Olga S. ;
Wu, Lawrence ;
Majsterek, Ireneusz ;
Herlyn, Meenhard ;
Fuchs, Serge Y. ;
Diehl, J. Alan .
PLOS GENETICS, 2016, 12 (12)