Exploiting synthetic chemistry with mesoionic rings:: Improvements achieved with thioisomunchnones

被引：31

作者：

Avalos, M ^{[1
]}

Babiano, R ^{[1
]}

Cintas, P ^{[1
]}

Jiménez, JL ^{[1
]}

Palacios, JC ^{[1
]}

机构：

[1] Univ Extremadura, Fac Ciencias, Dept Quim Organ, E-06071 Badajoz, Spain

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2005年 / 38卷 / 06期

关键词：

D O I：

10.1021/ar040212r

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The chemistry of mesoionic rings, especially their use as masked dipoles, has been a fruitful area of research since the late 1950s. With recent advances in the control of regio- and stereo chemistry, the dipolar cycloaddition led to widespread application. In this Account, we illustrate our contribution employing thioisomunchnones, a class of mesoionics that has found use in creating a series of heterocyclic systems hitherto inaccessible by conventional 1,3-dipolar cycloaddition. We also provide some rationalizations from computations and comment on future directions.

引用

页码：460 / 468

页数：9

共 36 条

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