Anxiety and depression:: Main determinants of health-related quality of life in Brazilian patients with Parkinson's disease

被引：97

作者：

Carod-Artal, Francisco Javier ^{[1
]}

Ziomkowski, Sofia ^{[1
]}

Mesquita, Hudson Mourao ^{[1
]}

Martinez-Martin, Pablo ^{[2
]}

机构：

[1] Sarah Network Rehabil Hosp, Sarah Hosp, Dept Neurol, BR-70330150 Brasilia, DF, Brazil

[2] Inst Salud Carlos III, Natl Ctr Epidemiol, Neuroepidemiol Unit, Madrid, Spain

来源：

PARKINSONISM & RELATED DISORDERS | 2008年 / 14卷 / 02期

关键词：

anxiety; comorbidity; depression; quality of life; mood disorders; Parkinson's disease;

D O I：

10.1016/j.parkreldis.2007.06.011

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Determinants of health-related quality of life (HRQoL) were assessed in 115 Brazilian patients (56.5% males; mean age 62.5 years) with Parkinson's disease (PD). Hoehn and Yahr (H&Y) staging, Scales for Outcomes in Parkinson's Disease-Motor Scale (SCOPA-MS), Cumulative Illness Rating Scale-Geriatrics, Hospital Anxiety and Depression Scale (HADS), Parkinson's Disease Questionnaire (PDQ-39)., and SCOPA-Psychosocial Questionnaire (SCOPA-PS) were applied. Median H&Y was 3 and the SCOPA-MS score was 25.6 +/- 13.1. The proportion of patients who scored >= 11 points in the HADS-Depression and HADS-Anxiety subscales were 47% and 30.4%, respectively. In the multivariate model, HADS-Anxiety or HADS-Depression (p<0.0001), disability (SCOPA-MS II) (P = 0.0001) and comorbidity (p = 0.0005) were independently associated to PDQ-39 and SCOPA-PS. Mood disturbances were the main determinants of HRQoL. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：102 / 108

页数：7

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