Further syphonosides from the sea hare Syphonota geographica and the sea-grass Halophila stipulacea

被引：22

作者：

Carbone, Marianna ^{[1
]}

Gavagnin, Margherita ^{[1
]}

Mollo, Ernesto ^{[1
]}

Bidello, Margherita ^{[1
]}

Roussis, Vassilios ^{[2
]}

Cimino, Guido ^{[1
]}

机构：

[1] CNR, Ist Chim Biomol, Via Campi Flegrei 34, I-80078 Naples, Italy

[2] Univ Athens, Sch Pharm, Dept Pharmacognosy & Chem Nat Prod, GR-15771 Athens, Greece

来源：

TETRAHEDRON | 2008年 / 64卷 / 01期

关键词：

marine natural products; halophila stipulacea; syphonola geographica; molluscs; macrocycles; glycoterpenoids;

D O I：

10.1016/j.tet.2007.10.071

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The unusual structural features of syphonoside (1), recently reported from the marine mollusc Syphonota geographica and its prey Halophila stipulacea, stimulated further investigations on the minor secondary metabolites of both organisms. The three novel macrocyclic glycoterpenoids 2-4, structurally related to the main co-occurring metabolite 1, have been isolated and chemically characterized mainly by NMR spectroscopic technique, and degradation methods. Compounds 2 and 3 were found only in the mollusc whereas compound 4 was isolated in trace quantities exclusively from the sea-grass. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：191 / 196

页数：6

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