A general method for the direct α-arylation of aldehydes with aryl bromides and chlorides

被引：106

作者：

Martin, Ruben ^{[1
]}

Buchwald, Stephen L. ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 38期

关键词：

aldehydes; arylation; homogeneous catalysis; P ligands; palladium;

D O I：

10.1002/anie.200703009

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Wide scope: A catalyst system able to efficiently perform the title reaction is described (see scheme). The high level of activity achieved allows for the synthesis of highly functionalized compounds with a wide variety of substitution patterns under very mild conditions. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7236 / 7239

页数：4

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