Glutamate transporters in neurologic disease

被引：241

作者：

Maragakis, NJ ^{[1
]}

Rothstein, JD ^{[1
]}

机构：

[1] Johns Hopkins Univ, Dept Neurol, Baltimore, MD 21287 USA

来源：

ARCHIVES OF NEUROLOGY | 2001年 / 58卷 / 03期

关键词：

D O I：

10.1001/archneur.58.3.365

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Glutamate is the primary excitatory amino acid neurotransmitter in the human brain. It is important in synaptic plasticity, learning, and development. Its activity at the synaptic cleft is carefully balanced by receptor inactivation and glutamate reuptake. When this balance is upset, excess glutamate can itself become neurotoxic.

引用

页码：365 / 370

页数：6

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