Direct amination of β-oxo esters

被引：18

作者：

Fioravanti, S ^{[1
]}

Morreale, A ^{[1
]}

Pellacani, L ^{[1
]}

Tardella, PA ^{[1
]}

机构：

[1] Univ Rome La Sapienza, Dipartimento Chim, I-00185 Rome, Italy

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 06期

关键词：

amination; keto acids and derivatives; amino acids and derivatives; carbamates;

D O I：

10.1016/S0040-4039(00)02200-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of NsONHCO(2)Et, in the presence of CaO, with beta -oxo esters gives the corresponding aminated products in yields up to 58%. A substrate carrying the Oppolzer sultam undergoes amination with 40% diastereoselectivity. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1171 / 1173

页数：3

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