Antioxidant activity of water-soluble chitosan derivatives

被引：524

作者：

Xie, WM ^{[1
]}

Xu, PX ^{[1
]}

Liu, Q ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 13期

关键词：

D O I：

10.1016/S0960-894X(01)00285-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Water-soluble chitosan derivatives were prepared by graft copolymerization of maleic acid sodium onto hydroxypropyl chitosan and carboxymethyl chitosan sodium. Their scavenging activities against hydroxyl radical OH were investigated by chemiluminescence technique. They exhibit IC50 values ranging from 246 to 498 mug/mL, which should be attributed to their different contents of hydroxyl and amino groups and different substituting groups. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1699 / 1701

页数：3

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