Quadruply gamma-cyclodextrin-linked cofacial porphyrin is synthesized from the one-pot reaction of pyrrole and acetylated gamma-cyclodextrin 6(A),6(E)-bisbenzaldehyde by the Lindsey's method, Deacetylation affords the water-soluble derivative. Their spectroscopic properties are also described. (C) 1999 Elsevier Science Ltd. All rights reserved.