The SecA subunit of Escherichia coli preprotein translocase is exposed to the periplasm

被引：28

作者：

Eichler, J ^{[1
]}

Wickner, W ^{[1
]}

机构：

[1] Dartmouth Coll, Sch Med, Dept Biochem, Hanover, NH 03755 USA

来源：

JOURNAL OF BACTERIOLOGY | 1998年 / 180卷 / 21期

关键词：

D O I：

10.1128/JB.180.21.5776-5779.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

SecA undergoes conformational changes during translocation, inserting domains into and across the membrane or enhancing the protease resistance of these domains. We now show that some SecA bound at SecYEG is accessible from the periplasm to a membrane-impermeant probe in cells with a permeabilized outer membrane but an intact plasma membrane.

引用

页码：5776 / 5779

页数：4

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