Recognizing and remodeling the nucleosome

被引:22
作者
Glatt, Sebastian [1 ]
Alfieri, Claudio [1 ]
Mueller, Christoph W. [1 ]
机构
[1] European Mol Biol Lab, Struct & Computat Biol Unit, D-69117 Heidelberg, Germany
关键词
HISTONE H3 TAIL; CORE PARTICLE; CHROMATIN MODIFICATIONS; ANGSTROM RESOLUTION; CRYSTAL-STRUCTURE; STRUCTURAL BASIS; PHD FINGER; RECOGNITION; COMPLEX; BROMODOMAIN;
D O I
10.1016/j.sbi.2011.02.003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The X-ray structure of the nucleosome core particle (NCP) has been a major milestone in the structural biology of chromatin. Since, our understanding how NCPs interact with multiple partners has been extending from single chromatin-binding domains recognizing post-translational modifications (PTMs) in histone tails towards the recognition of higher-order chromatin structure by multi-subunit chromatin remodeling complexes. The current review summarizes recent progress in the structural biology of nucleosome-recognition from chromatin-binding domains to multi-protein remodeling complexes.
引用
收藏
页码:335 / 341
页数:7
相关论文
共 50 条
  • [1] The Swi2/Snf2 Bromodomain Is Important for the Full Binding and Remodeling Activity of the SWI/SNF Complex on H3-and H4-acetylated Nucleosomes
    Awad, Salma
    Hassan, Ahmed H.
    [J]. RECENT ADVANCES IN CLINICAL ONCOLOGY, 2008, 1138 : 366 - 375
  • [2] The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA
    Barbera, AJ
    Chodaparambil, JV
    Kelley-Clarke, B
    Joukov, V
    Walter, JC
    Luger, K
    Kaye, KM
    [J]. SCIENCE, 2006, 311 (5762) : 856 - 861
  • [3] The folding and unfolding of eukaryotic chromatin
    Bassett, Andrew
    Cooper, Sarah
    Wu, Chenyi
    Travers, Andrew
    [J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 2009, 19 (02) : 159 - 165
  • [4] The complex language of chromatin regulation during transcription
    Berger, Shelley L.
    [J]. NATURE, 2007, 447 (7143) : 407 - 412
  • [5] Dynamics of nucleosome remodelling by individual ACF complexes
    Blosser, Timothy R.
    Yang, Janet G.
    Stone, Michael D.
    Narlikar, Geeta J.
    Zhuang, Xiaowei
    [J]. NATURE, 2009, 462 (7276) : 1022 - U79
  • [6] Mechanisms of ATP-dependent nucleosome sliding
    Bowman, Gregory D.
    [J]. CURRENT OPINION IN STRUCTURAL BIOLOGY, 2010, 20 (01) : 73 - 81
  • [7] Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2
    Charlop-Powers, Zachary
    Zeng, Lei
    Zhang, Qiang
    Zhou, Ming-Ming
    [J]. CELL RESEARCH, 2010, 20 (05) : 529 - 538
  • [8] The Biology of Chromatin Remodeling Complexes
    Clapier, Cedric R.
    Cairns, Bradley R.
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, 2009, 78 : 273 - 304
  • [9] Domain architecture of the catalytic subunit in the ISW2-nucleosome complex
    Dang, Weiwei
    Bartholomew, Blaine
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2007, 27 (23) : 8306 - 8317
  • [10] Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 Å resolution
    Davey, CA
    Sargent, DF
    Luger, K
    Maeder, AW
    Richmond, TJ
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2002, 319 (05) : 1097 - 1113