Cyclization of polyenes.: 58.: Synthesis of longithorone B, a sixteen-membered farnesylated p-benzoquinone

被引：19

作者：

Kato, T ^{[1
]}

Nagae, K ^{[1
]}

Hoshikawa, M ^{[1
]}

机构：

[1] Sci Univ Tokyo, Fac Sci, Dept Chem, Shinjuku Ku, Tokyo 1628601, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(99)00049-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The intramolecular coupling reactions at the C-1position of the 10Z-farnesyl moiety appended at the 2'-position of 4'-methoxy phenol derivatives were examined with the aid of Hf(OTf)(4)and LiClO4. When the phenol was protected with a TBDMS group, meta coupling predominated while para coupling occurred efficiently when protected with a pivaloyl group. The para-coupled product was transformed to longithorone B, recently isolated from a tunicate. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1941 / 1944

页数：4

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