Pros and cons of the use of antihistamines in managing allergic rhinitis

被引：14

作者：

Day, J ^{[1
]}

机构：

[1] Queens Univ, Dept Med, Div Allergy & Immunol, Kingston, ON K7L 3N6, Canada

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 1999年 / 103卷 / 03期

关键词：

D O I：

10.1016/S0091-6749(99)70219-8

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Histamine H-1-receptor antagonists are generally considered first-line therapy for the management of allergic rhinitis, Other than histamine antagonism, several of the second-generation antihistamines have also shown inhibitory effects on chemical mediators of inflammation such as leukotrienes, prostaglandins, and kinins, This article reviews the pharmacology, clinical use, and side effect profiles of the commonly used H-1-receptor antagonists.

引用

页码：S395 / S399

页数：5

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