Structure-Activity Relationships and Rational Design Strategies for Radical-Scavenging Antioxidants

被引：104

作者：

Zhang, Hong-Yu ^{[1
]}

机构：

[1] Shandong Univ Technol, Shandong Prov Res Ctr Bioinformat Engn & Tech, Ctr Adv Study, Zibo 255049, Peoples R China

来源：

CURRENT COMPUTER-AIDED DRUG DESIGN | 2005年 / 1卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Antioxidant; radical; structure-activity relationship; rational design;

D O I：

10.2174/1573409054367691

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In the past two decades, there has been growing interest in finding novel and non-toxic antioxidants to meet the requirements in chemical, food and pharmaceutical industries. To accelerate the antioxidant discovery process, various theoretical methods have been employed to investigate the structure-activity relationships of antioxidants. Accordingly, some rational-design strategies for antioxidants have been proposed and applied in practice. This review summarizes the current knowledge on this topic, which will be helpful to direct the practice in related fields.

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收藏

页码：257 / 273

页数：17

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