Compact model for multi-phase liquid-liquid flows in micro-fluidic devices

被引:59
作者
Jousse, F [1 ]
Lian, GP [1 ]
Janes, R [1 ]
Melrose, J [1 ]
机构
[1] Unilever Corp Res, Sharnbrook MK44 1LQ, Beds, England
关键词
D O I
10.1039/b416666c
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We present a compact model describing the laminar flow of viscous multiphase fluids in microchannel networks. We apply this model to the flow of 2 immiscible fluids representing typically oil and water, in a network of micro-channels comprising one inlet for each fluid splitting into 2 branches meeting at a T-junction, where the 2 phases are combined before exiting the network through two outlets. This network is akin to an electrical "Wheatstone bridge'' and represents a simplified interdigital micro-reactor, where the fluids to be mixed are separated into smaller branches and later re-combined together. We show from an analytical solution and a computational modelling that fluid flow inside this network is very sensitive to small differences in fluid resistance between the various branches of the network, which may lead to catastrophic error in fluid distribution between the various branches that can have a profound effect on mixing. These errors depend on the viscosity difference between the fluids, on the processing conditions, and also on the geometric resistance parameters of the various channels. Increasing the resistance of the distribution channels upstream of the fluid junctions allows minimisation of the distribution errors. Interaction between the fluids can also lead to transients that are orders of magnitude longer than the flooding time of the channels. This may be exploited to provide impedance-like terms in flui-logic operations.
引用
收藏
页码:646 / 656
页数:11
相关论文
共 43 条
[1]   Steady flows in networks of microfluidic channels: building on the analogy with electrical circuits [J].
Ajdari, A .
COMPTES RENDUS PHYSIQUE, 2004, 5 (05) :539-546
[2]   Formation of dispersions using "flow focusing" in microchannels [J].
Anna, SL ;
Bontoux, N ;
Stone, HA .
APPLIED PHYSICS LETTERS, 2003, 82 (03) :364-366
[3]   Reaction-diffusion dynamics:: Confrontation between theory and experiment in a microfluidic reactor -: art. no. 060104 [J].
Baroud, CN ;
Okkels, F ;
Ménétrier, L ;
Tabeling, P .
PHYSICAL REVIEW E, 2003, 67 (06) :4
[4]   Small-scale free surface flows with breakup: Drop formation and emerging applications [J].
Basaran, OA .
AICHE JOURNAL, 2002, 48 (09) :1842-1848
[5]   A magneto-hydrodynamically controlled fluidic network [J].
Bau, HH ;
Zhu, JZ ;
Qian, SZ ;
Xiang, Y .
SENSORS AND ACTUATORS B-CHEMICAL, 2003, 88 (02) :205-216
[6]   Study of microfluidic components:: Application to a volumetric micropump [J].
Bendib, S ;
Français, O .
HOUILLE BLANCHE-REVUE INTERNATIONALE DE L EAU, 2003, (05) :73-83
[7]   Detailed physics, predictive capabilities and macroscopic consequences for pore-network models of multiphase flow [J].
Blunt, MJ ;
Jackson, MD ;
Piri, M ;
Valvatne, PH .
ADVANCES IN WATER RESOURCES, 2002, 25 (8-12) :1069-1089
[8]   THE MOTION OF LONG BUBBLES IN TUBES [J].
BRETHERTON, FP .
JOURNAL OF FLUID MECHANICS, 1961, 10 (02) :166-188
[9]   Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets [J].
Bringer, MR ;
Gerdts, CJ ;
Song, H ;
Tice, JD ;
Ismagilov, RF .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2004, 362 (1818) :1087-1104
[10]   The intensification of rapid reactions in multiphase systems using slug flow in capillaries [J].
Burns, JR ;
Ramshaw, C .
LAB ON A CHIP, 2001, 1 (01) :10-15