Insect sex-pheromone signals mediated by specific combinations of olfactory receptors

被引：414

作者：

Nakagawa, T

Sakurai, T

Nishioka, T ^{[3
]}

Touhara, K

机构：

[1] Univ Tokyo, Grad Sch Frontier Sci, Dept Integrated Biosci, Chiba 2778562, Japan

[2] Kyoto Univ, Grad Sch Agr, Div Appl Biosci, Kyoto 6068502, Japan

[3] Kyoto Univ, Grad Sch Agr, Div Appl Life Sci, Kyoto 6068502, Japan

[4] Japan Sci & Technol Agcy, Core Res Evolut Sci & Technol, Kawaguchi 3320012, Japan

来源：

SCIENCE | 2005年 / 307卷 / 5715期

关键词：

D O I：

10.1126/science.1106267

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We describe two mate-specific olfactory receptors (ORs) in the silk moth, Bombyx mori, that are mutually exclusively expressed in a pair of adjacent pheromone-sensitive neurons of mate antennae: One is specifically tuned to bombykol, the sex pheromone, and the other to bombykal, its oxidized form. Both pheromone ORs are coexpressed with an OR from the highly conserved insect OR subfamily. This coexpression promotes the functional expression of pheromone receptors and confers ligand-stimulated nonselective cation channel activity. The same effects were also observed for general ORs. Both odorant and pheromone signaling pathways are mediated by means of a common mechanism in insects.

引用

页码：1638 / 1642

页数：5

共 25 条

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