The odor coding system of Drosophila

被引：138

作者：

Hallem, EA ^{[1
]}

Carlson, JR ^{[1
]}

机构：

[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA

来源：

TRENDS IN GENETICS | 2004年 / 20卷 / 09期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/j.tig.2004.06.015

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Our understanding of the molecular and cellular organization of the Drosophila melanogaster olfactory system has increased dramatically in recent years. A large family of similar to60 odorant receptors has been identified, and many of these receptors have been functionally characterized. The odor responses of olfactory receptor neurons have been characterized, and much has been learned about how odors are represented in olfactory centers in the brain. The circuitry of the olfactory system has been studied in detail, and the developmental mechanisms that specify the wiring and functional diversity of olfactory neurons are becoming increasingly well understood. Thus, functional, anatomical and developmental studies are rapidly being integrated to form a unified picture of odor coding in this model olfactory system.

引用

页码：453 / 459

页数：7

共 83 条

[1] Dock and Pak regulate olfactory axon pathfinding in Drosophila [J].

Ang, LH ;

Kim, J ;

Stepensky, V ;

Hing, H .

DEVELOPMENT, 2003, 130 (07) :1307-1316

[2] GENETICS OF OLFACTORY BEHAVIOR IN DROSOPHILA-MELANOGASTER [J].

AYYUB, C ;

PARANJAPE, J ;

RODRIGUES, V ;

SIDDIQI, O .

JOURNAL OF NEUROGENETICS, 1990, 6 (04) :243-262

[3] COMPARTMENT BOUNDARIES AND THE CONTROL OF DROSOPHILA LIMB PATTERN BY HEDGEHOG PROTEIN [J].

BASLER, K ;

STRUHL, G .

NATURE, 1994, 368 (6468) :208-214

[4] Olfactory neurons expressing identified receptor genes project to subsets of glomeruli within the antennal lobe of Drosophila melanogaster [J].

Bhalerao, S ;

Sen, A ;

Stocker, R ;

Rodrigues, V .

JOURNAL OF NEUROBIOLOGY, 2003, 54 (04) :577-592

[5]

BRAND AH, 1993, DEVELOPMENT, V118, P401

[6] A putative Drosophila pheromone receptor expressed in male-specific taste neurons is required for efficient courtship [J].

Bray, S ;

Amrein, H .

NEURON, 2003, 39 (06) :1019-1029

[7] A NOVEL MULTIGENE FAMILY MAY ENCODE ODORANT RECEPTORS - A MOLECULAR-BASIS FOR ODOR RECOGNITION [J].

BUCK, L ;

AXEL, R .

CELL, 1991, 65 (01) :175-187

[8] Olfaction in Drosophila: From odor to behavior [J].

Carlson, JR .

TRENDS IN GENETICS, 1996, 12 (05) :175-180

[9] Drosophila Gr5a encodes a taste receptor tuned to trehalose [J].

Chyb, S ;

Dahanukar, A ;

Wickens, A ;

Carlson, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 :14526-14530

[10]

Clyne Peter, 1997, Invertebrate Neuroscience, V3, P127, DOI 10.1007/BF02480367

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