COMPARTMENT BOUNDARIES AND THE CONTROL OF DROSOPHILA LIMB PATTERN BY HEDGEHOG PROTEIN

被引：770

作者：

BASLER, K ^{[1
]}

STRUHL, G ^{[1
]}

机构：

[1] COLUMBIA UNIV, COLL PHYS & SURG, HOWARD HUGHES MED INST, NEW YORK, NY 10032 USA

来源：

NATURE | 1994年 / 368卷 / 6468期

关键词：

D O I：

10.1038/368208a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Drosophila limbs are subdivided into anterior and posterior compartments which derive from adjacent cell populations founded early in development. Evidence is now provided that posterior cells organize growth and cell patterning in both compartments by secreting hedgehog protein and that hedgehog protein acts indirectly by inducing neighbouring anterior cells to secrete decapentaplegic or wingless protein.

引用

页码：208 / 214

页数：7

共 72 条

[1]

ANDERSON R, 1993, DEVELOPMENT, V117, P1421

[2]

ARIAS AM, 1988, DEVELOPMENT, V103, P157

[3] EMBRYONIC AND IMAGINAL REQUIREMENTS FOR WINGLESS, A SEGMENT-POLARITY GENE IN DROSOPHILA [J].

BAKER, NE .

DEVELOPMENTAL BIOLOGY, 1988, 125 (01) :96-108

[4]

BEJSOVEC A, 1991, DEVELOPMENT, V113, P471

[5]

BLACKMAN RK, 1991, DEVELOPMENT, V111, P657

[6]

BLAIR SS, 1993, DEVELOPMENT, V119, P339

[7] REPLICATION AND RECOMBINATION FUNCTIONS ASSOCIATED WITH THE YEAST PLASMID, 2-MU CIRCLE [J].

BROACH, JR ;

HICKS, JB .

CELL, 1980, 21 (02) :501-508

[8]

CABRERA CV, 1987, CELL, V50, P569

[9] AXIS SPECIFICATION IN THE DEVELOPING DROSOPHILA APPENDAGE - THE ROLE OF WINGLESS, DECAPENTAPLEGIC, AND THE HOMEOBOX GENE ARISTALESS [J].

CAMPBELL, G ;

WEAVER, T ;

TOMLINSON, A .

CELL, 1993, 74 (06) :1113-1123

[10] A WINGLESS-DEPENDENT POLAR COORDINATE SYSTEM IN DROSOPHILA IMAGINAL DISKS [J].

COUSO, JP ;

BATE, M ;

MARTINEZARIAS, A .

SCIENCE, 1993, 259 (5094) :484-489

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