COMPARTMENT BOUNDARIES AND THE CONTROL OF DROSOPHILA LIMB PATTERN BY HEDGEHOG PROTEIN

被引:770
作者
BASLER, K [1 ]
STRUHL, G [1 ]
机构
[1] COLUMBIA UNIV, COLL PHYS & SURG, HOWARD HUGHES MED INST, NEW YORK, NY 10032 USA
关键词
D O I
10.1038/368208a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Drosophila limbs are subdivided into anterior and posterior compartments which derive from adjacent cell populations founded early in development. Evidence is now provided that posterior cells organize growth and cell patterning in both compartments by secreting hedgehog protein and that hedgehog protein acts indirectly by inducing neighbouring anterior cells to secrete decapentaplegic or wingless protein.
引用
收藏
页码:208 / 214
页数:7
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