Use of the non-aldol aldol process in the synthesis of the C1-C11 fragment of the tedanolides: use of lactol ethers in place of tetrahydrofurans

被引：26

作者：

Jung, ME ^{[1
]}

Lee, CP ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 50期

基金：

美国国家卫生研究院;

关键词：

non-aldol aldol; polypropionate synthesis; lactol methyl ethers;

D O I：

10.1016/S0040-4039(00)01726-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of a lactol methyl ether 23 in place of the simple tetrahydrofuran 11 allows for the high yielding non-aldol aldol process to occur without concomitant tetrahydropyran formation (cf 13) to give the desired product 24 in good yield. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：9719 / 9723

页数：5

共 25 条

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