Multiple folate enzyme inhibition: Mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA)

被引:127
作者
Shih, C [1 ]
Habeck, LL [1 ]
Mendelsohn, LG [1 ]
Chen, VJ [1 ]
Schulz, RM [1 ]
机构
[1] Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA
来源
ADVANCES IN ENZYME REGULATION, VOL 38 | 1998年 / 38卷
关键词
D O I
10.1016/S0065-2571(97)00017-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:135 / 152
页数:18
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