Engineering of secondary metabolite pathways

被引：45

作者：

Mijts, BN ^{[1
]}

Schmidt-Dannert, C ^{[1
]}

机构：

[1] Univ Minnesota, Dept Biochem Mol Biol & Biophys, Gortner Lab 140, St Paul, MN 55108 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2003年 / 14卷 / 06期

关键词：

D O I：

10.1016/j.copbio.2003.09.009

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Nature produces an astonishing wealth of secondary metabolites with important biological functions. To access this diversity of structurally complex chemical compounds for industrial and biomedical applications, cells have been engineered to produce higher levels and/or novel compounds that were previously inaccessible. Recent examples of metabolic and combinatorial engineering illustrate different strategies for the production of secondary metabolites in microbial cells.

引用

页码：597 / 602

页数：6

共 48 条

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