Extreme Makeover: Converting One Cell into Another

被引：181

作者：

Zhou, Qiao ^{[1
]}

Melton, Douglas A. ^{[1
]}

机构：

[1] Harvard Univ, Harvard Stem Cell Inst, Dept Stem Cell & Regenerat Biol, HHMI, Cambridge, MA 02138 USA

来源：

CELL STEM CELL | 2008年 / 3卷 / 04期

关键词：

D O I：

10.1016/j.stem.2008.09.015

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Cells of adult mammals can be converted (reprogrammed) to new cells. In one approach, adult cells are converted to pluripotent stem cells, followed by differentiation to regenerate new cell types. Alternatively, adult cells may be directly converted into other mature cells or progenitors. We discuss and compare these two approaches with particular emphasis on the latter and its relevance for regenerative medicine.

引用

页码：382 / 388

页数：7

共 47 条

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