Bacterial resistance to heavy metals and metalloids

被引：83

作者：

Rosen, BP

机构：

[1] Dept. of Biochem. and Molec. Biology, Wayne State University, School of Medicine, Detroit, MI 48201

来源：

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY | 1996年 / 1卷 / 04期

关键词：

metal resistance; reductase; pump; carrier; metalloregulation;

D O I：

10.1007/s007750050053

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bacteria have evolved various types of resistance mechanisms to toxic metals and metalloids including mercury, cadmium/zinc, copper/silver and arsenic/antimony. Active efflux of the metal is a frequently utilized stratagem, lowering the intracellular concentration to subtoxic levels. Reduction to a less toxic form or to a form recognized by an efflux system also occurs. Sequestration of metals has also been observed. In bacteria, each of these resistance systems is transcriptionally regulated by the metal.

引用

页码：273 / 277

页数：5

共 39 条

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