QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations

被引：335

作者：

Yang, Jian ^{[1
]}

Hu, Chengcheng ^{[2
]}

Hu, Han ^{[1
]}

Yu, Rongdong ^{[2
]}

Xia, Zhen ^{[1
]}

Ye, Xiuzi ^{[2
]}

Zhu, Jun ^{[1
]}

机构：

[1] Zhejiang Univ, Inst Bioinformat, Hangzhou 310029, Peoples R China

[2] Zhejiang Univ, Comp Graph & Imaging Lab, Hangzhou 310027, Peoples R China

来源：

BIOINFORMATICS | 2008年 / 24卷 / 05期

基金：

国家高技术研究发展计划(863计划);

关键词：

D O I：

10.1093/bioinformatics/btm494

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

QTLNetwork is a software package for mapping and visualizing the genetic architecture underlying complex traits for experimental populations derived from a cross between two inbred lines. It can simultaneously map quantitative trait loci (QTL) with individual effects, epistasis and QTLenvironment interaction. Currently, it is able to handle data from F-2, backcross, recombinant inbred lines and double-haploid populations, as well as populations from specific mating designs (immortalized F-2 and BCnFn populations). The Windows version of QTLNetwork was developed with a graphical user interface. Alternatively, the command-line versions have the facility to be run in other prevalent operating systems, such as Linux, Unix and MacOS.

引用

页码：721 / 723

页数：3

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