Multifunctional, Biocompatible Supramolecular Hydrogelators Consist Only of Nucleobase, Amino Acid, and Glycoside

被引：111

作者：

Li, Xinming ^{[1
]}

Kuang, Yi ^{[1
]}

Shi, Junfeng ^{[1
]}

Gao, Yuan ^{[1
]}

Lin, Hsin-Chieh ^{[1
]}

Xu, Bing ^{[1
]}

机构：

[1] Brandeis Univ, Dept Chem, Waltham, MA 02454 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 43期

关键词：

SOLID-PHASE SYNTHESIS; ENZYMATIC FORMATION; CIRCULAR-DICHROISM; GENE-TRANSFER; PEPTIDES; NANOFIBERS; COMPLEX; DESIGN; WATER; SUPERSTRUCTURES;

D O I：

10.1021/ja208456k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The integration of nucleobase, amino acid, and glycoside into a single molecule results in a novel class of supramolecular hydrogelators, which not only exhibit biocompatibility and biostability but also facilitate the entry of nucleic acids into cytosol and nuclei of cells. This work illustrates a simple way to generate an unprecedented molecular architecture from the basic biological building blocks for the development of sophisticated soft nanomaterials, including supramolecular hydrogels.

引用

页码：17513 / 17518

页数：6

共 86 条

[81] Supramolecular hydrogels based on β-amino acid derivatives [J].