Peptide and protein folding

被引：39

作者：

Chasse, GA

Rodriguez, AM

Mak, ML

Deretey, E

Perczel, A

Sosa, CP

Enriz, RD

Csizmadia, IG ^{[1
]}

机构：

[1] Univ Toronto, Lash Miller Chem Lab, Dept Chem, 60 George St, Toronto, ON M5S 3H6, Canada

[2] Univ Nacl San Luis, Dept Quim, RA-5700 San Luis, Argentina

[3] Eotvos Lorand Univ, Dept Organ Chem, H-1117 Budapest, Hungary

[4] Cray Res Inc, Eagan, MN 55121 USA

来源：

JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM | 2001年 / 537卷

关键词：

peptide folding; protein folding; reductionism and holism;

D O I：

10.1016/S0166-1280(00)00687-4

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Ab initio peptide folding, and its role in the reductionistic approach towards the understanding of protein folding are discussed from the points of view of past, present and possible future developments. It is believed that after the initial holistic approach, we are now at a new epoch, which will be dominated by reductionism. New quantitative mathematical models will be the result of the reductionistic approach that will lead toward a new, more sophisticated holistic era. (C) 2001 Elsevier Science B.V. All rights reserved.

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页码：319 / 361

页数：43

相关论文

共 186 条

[21] Chemical physics of protein folding [J].

Brooks, CL ;

Gruebele, M ;

Onuchic, JN ;

Wolynes, PG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (19) :11037-11038

[22] SYNTHESE DER Y-POLY-(Y-L-GLUTAMYL-D-GLUTAMINSAURE) EIN BEITRAG UR KONSTITUTIONSERMITTLUNG DES SUBTILLIS-POLYPEPTIDS [J].

BRUCKNER, V ;

WEIN, J ;

KAJTAR, M ;

KOVACS, J .

NATURWISSENSCHAFTEN, 1957, 44 (04) :89-90

[23] SYNTHESE DER A.Y-POLY-D-GLUTAMINSAURE [J].

BRUCKNER, V ;

SZEKERKE, M ;

KOVACS, J .

NATURWISSENSCHAFTEN, 1957, 44 (04) :90-90

[24] SYNTHESE DER ALPHA-L-POLYGLUTAMINSAURE [J].

BRUCKNER, V ;

KOVACS, J ;

KOVACS, K .

NATURWISSENSCHAFTEN, 1952, 39 (16) :380-380

[25] THE STRUCTURE OF NATIVE POLY-D-GLUTAMIC ACID .4. THE SYNTHESIS OF POLY-L-GLUTAMINE AND THE HOFMANN DEGRADATION THEREOF [J].

BRUCKNER, V ;

KOVACS, J ;

KOVACS, K .

JOURNAL OF THE CHEMICAL SOCIETY, 1953, (MAY) :1512-1514

[26] THE STRUCTURE OF NATIVE POLY-D-GLUTAMIC ACID .3. [J].

BRUCKNER, V ;

KOVACS, J ;

NAGY, H .

JOURNAL OF THE CHEMICAL SOCIETY, 1953, (JAN) :148-150

[27] SYNTHESE DES IMMUNSPEZIFISCHEN HAPTENS (DER NATURLICHEN POLY-D-GLUTAMINSAURE) DER ANTHRAX-SUBTILIS-BAZILLENGRUPPE [J].

BRUCKNER, V ;

WEIN, J ;

KAJTAR, M ;

KOVACS, J .

NATURWISSENSCHAFTEN, 1955, 42 (16) :463-463

[28] UBER DIE STRUKTUR DER NATIVEN D-POLYGLUTAMINSAURE [J].

BRUCKNER, V ;

KOVACS, J ;

KOVACS, K ;

NAGY, H .

EXPERIENTIA, 1953, 9 (02) :63-64

[29] Infrared absorption studies. XI. NH-N and NH-O bonds [J].

Buswell, AM ;

Downing, JR ;

Rodebush, WH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1940, 62 :2759-2765

[30]

CHEAM TC, 1989, J MOL STRUC-THEOCHEM, V57, P15, DOI 10.1016/0166-1280(89)85023-7

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