Uptake of plutonium by the human liver

被引：17

作者：

Newton, D ^{[1
]}

Talbot, RJ ^{[1
]}

Kang, C ^{[1
]}

Warner, AJ ^{[1
]}

机构：

[1] AEA Technol, Biomed Res, Didcot OX11 0RA, Oxon, England

来源：

RADIATION PROTECTION DOSIMETRY | 1998年 / 80卷 / 04期

关键词：

D O I：

10.1093/oxfordjournals.rpd.a032558

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The hepatic uptake of Pu-237 in 12 healthy subjects who received it intravenously as Pu(IV) citrate is reported. The results were derived from the response of a scintillation counter viewing the right lateral surfaces of the lower thorax; calibration for individual subjects was performed with Pu-237-loaded phantoms based on anatomical data from magnetic resonance imaging. The highest levels (mean 73 +/- 12 (sd) % of injection) were reached variously after 7-230 days, with no conclusive evidence of a subsequent reduction: half of the accumulation occurred within 1-2 days. This uptake is much greater than predicted by the ICRP's present or previous metabolic models for plutonium, but the excess is strongly corroborated by other data from this study.

引用

页码：385 / 395

页数：11

共 25 条

[11]

*INT COMM RAD PROT, 1987, ANN ICRP, V18

[12]

International Commission on Radiological Protection, 1975, INT COMM RAD PROT PU, V23

[13] Interspecies comparison of lung clearance using monodisperse terbium oxide particles [J].

Kreyling, WG ;

Hodgson, A ;

Guilmette, RA ;

Scarlett, C ;

Badmin, A ;

Stradling, G .

RADIATION PROTECTION DOSIMETRY, 1998, 79 (1-4) :241-243

[14] DISTRIBUTION AND EXCRETION OF PLUTONIUM ADMINISTERED INTRAVENOUSLY TO MAN [J].

LANGHAM, WH ;

BASSETT, SH ;

HARRIS, PS ;

CARTER, RE .

HEALTH PHYSICS, 1980, 38 (06) :1031-1060

[15]

LEGGETT R, COMMUNICATION

[16]

MCINROY JF, 1989, RADIAT PROT DOSIM, V26, P151

[17] MEASUREMENT OF CALIFORNIUM-252 IN-VIVO [J].

NEWTON, D ;

EAGLE, MC .

HEALTH PHYSICS, 1972, 23 (06) :817-+

[18] METABOLISM OF INJECTED BARIUM IN 6 HEALTHY-MEN [J].

NEWTON, D ;

HARRISON, GE ;

KANG, C ;

WARNER, AJ .

HEALTH PHYSICS, 1991, 61 (02) :191-201

[19] Sex-related differences in the human metabolism of plutonium [J].

Talbot, RJ ;

Newton, D ;

Dmitriev, SN .

RADIATION PROTECTION DOSIMETRY, 1997, 71 (02) :107-121

[20] METABOLISM OF INJECTED PLUTONIUM IN 2 HEALTHY-MEN [J].

TALBOT, RJ ;

NEWTON, D ;

WARNER, AJ .

HEALTH PHYSICS, 1993, 65 (01) :41-46

← 1 2 3 →