Domino addition/annulation of δ-alkynylaldehydes and oxygen nucleophiles:: a new entry to [1,4]oxazino[4,3-a]indoles

被引：40

作者：

Abbiati, G ^{[1
]}

Canevari, V ^{[1
]}

Caimi, S ^{[1
]}

Rossi, E ^{[1
]}

机构：

[1] Univ Milan, Fac Farm, Ist Chim Organ Alessandro Marchesini, I-20133 Milan, Italy

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 42期

关键词：

1-alkynyl-1H-indole-2-carbaldehydes; 1,4]oxazino[4,3-a]-indole; domino addition/annulation; alcohol; sodium;

D O I：

10.1016/j.tetlet.2005.08.102

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The unusual [1,4]oxazino[4,3-a]indole nucleus was prepared, under mild reaction conditions, by reacting 1-alkynyl-1H-indole-2-carbaldehydes with various alkoxides, generated in situ from the corresponding alkyl, benzyl, allyl and propargyl alcohols. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：7117 / 7120

页数：4

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