Novel dithia-aza-norbornanes as 'Stiff' bicyclic dithiazines

被引：1

作者：

Kurchan, AN ^{[1
]}

Wade, E ^{[1
]}

Kutateladze, AG ^{[1
]}

机构：

[1] Univ Denver, Dept Chem & Biochem, Denver, CO 80208 USA

来源：

SYNLETT | 2003年 / 11期

关键词：

heterocycles; sulfur; carbanions; nucleophilic additions; diastereoselectivity; desulfurization;

D O I：

10.1055/s-2003-41431

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of lithiated 4,5-dihydro-1,3,5-dithiazines to in situ generated N-silylimines in THF produces 2-(alpha-aminoalkyl)dithiazines, which rearrange into 3,5-dithia-1-azabicyclo[2.2.1]heptanes upon aqueous workup. These novel bicyclic dithiazines can in turn be lithiated at the position 4 and added to carbonyl compounds.

引用

页码：1731 / 1733

页数：3

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