Sweet secrets of synthesis

被引:40
作者
Davies, GJ [1 ]
机构
[1] Univ York, Dept Chem, Struct Biol Lab, York YO10 5DD, N Yorkshire, England
关键词
D O I
10.1038/84198
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The crystal structure of a 'retaining' glycosyltransferase provides the first view of cc-glycosidic bond synthesis using activated nucleotide sugars.
引用
收藏
页码:98 / 100
页数:3
相关论文
共 21 条
  • [1] [Anonymous], ACTIVE LEARNING
  • [2] Structure of the nucleotide-diphospho-sugar transferase, SpsA from Bacillus subtilis, in native and nucleotide-complexed forms
    Charnock, SJ
    Davies, GJ
    [J]. BIOCHEMISTRY, 1999, 38 (20) : 6380 - 6385
  • [3] Coutinho PM, 1999, ROY SOC CH, P3
  • [4] DAVIES G, 1997, COMPREHENSIVE BIOL C, V1, P119
  • [5] Snapshots along an enzymatic reaction coordinate:: Analysis of a retaining β-glycoside hydrolase
    Davies, GJ
    Mackenzie, L
    Varrot, A
    Dauter, M
    Brzozowski, AM
    Schülein, M
    Withers, SG
    [J]. BIOCHEMISTRY, 1998, 37 (34) : 11707 - 11713
  • [6] Trapped in the act of catalysis
    Davies, GJ
    Wilson, KS
    [J]. NATURE STRUCTURAL BIOLOGY, 1999, 6 (05) : 406 - 408
  • [7] Crystal structures of the bovine β4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactose
    Gastinel, LN
    Cambillau, C
    Bourne, Y
    [J]. EMBO JOURNAL, 1999, 18 (13) : 3546 - 3557
  • [8] The 1.9 Å crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis
    Ha, S
    Walker, D
    Shi, YG
    Walker, S
    [J]. PROTEIN SCIENCE, 2000, 9 (06) : 1045 - 1052
  • [9] Glycoside hydrolases and glycosyltransferases. Families, modules, and implications for genomics
    Henrissat, B
    Davies, GJ
    [J]. PLANT PHYSIOLOGY, 2000, 124 (04) : 1515 - 1519
  • [10] Illuminating the ancient retainer
    Kirby, AJ
    [J]. NATURE STRUCTURAL BIOLOGY, 1996, 3 (02): : 107 - 108