One-pot synthesis of 2-(2-hydroxyaryl)quinolines:: reductive coupling reactions of 2′-hydroxy-2-nitrochalcones

被引：24

作者：

Barros, AIRNA

Silva, AMS ^{[1
]}

机构：

[1] Univ Aveiro, Dept Chem, P-3810193 Aveiro, Portugal

[2] Univ Tras Montes & Alto Douro, Dept Chem, P-5001911 Vila Real, Portugal

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 31期

关键词：

2-(2-hydroxyaryl)quinolines; 2-(2-hydroxyaryl)quinolines-N-oxides; 2 '-hydroxy-2-nitrochalcones; reduction; cyclodehydration;

D O I：

10.1016/S0040-4039(03)01374-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot synthesis of novel 2-(2-hydroxyaryl)quinolines have been developed from the intramolecular reductive coupling reactions of 2'-hydroxy-2-nitrochalcones, induced by stannous chloride in acidic medium (HCl/AcOH). In some cases these transformations can be performed with ammonium formate/Pd-C in methanol. (C) 2003 Elsevier Ltd. All rights reserved.

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收藏

页码：5893 / 5896

页数：4

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