Staphylococcal IgM Enzyme-Linked Immunosorbent Assay for Diagnosis of Periprosthetic Joint Infections

被引：16

作者：

Artini, Marco ^{[1
]}

Romano, Carlo ^{[2
]}

Manzoli, Lamberto ^{[3
]}

Scoarughi, Gian Luca ^{[1
]}

Papa, Rosanna ^{[1
]}

Meani, Enzo ^{[4
]}

Drago, Lorenzo ^{[2
]}

Selan, Laura ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dept Publ Hlth & Infect Dis, I-00185 Rome, Italy

[2] IRCCS Galeazzi Orthopaed Inst, Milan, Italy

[3] Univ G DAnnunzio, Sect Epidemiol & Publ Hlth, Chieti, Italy

[4] G Pini Orthopaed Inst, Milan, Italy

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 01期

关键词：

D O I：

10.1128/JCM.01836-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Delayed orthopedic joint prosthesis infections (DOJP-Is) due to staphylococci frequently result in prosthetic revision. Specific and noninvasive diagnostic tests are unavailable, and DOJP-Is are commonly diagnosed at advanced stages of disease. An enzyme-linked immunosorbent assay (ELISA) was developed to detect serum antibodies against staphylococcal slime polysaccharide antigens. Using a cutoff of 0.35 ELISA units, the test showed a specificity of 95.1% (95% confidence interval [CI], 85.4 to 98.7%) and a sensitivity of 89.7% (71.5 to 97.3%) on a sample of 90 individuals.

引用

页码：423 / 425

页数：3

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