Steric control of oxygenation regiochemistry in soybean lipoxygenase-1

被引:94
作者
Knapp, MJ [1 ]
Seebeck, FP [1 ]
Klinman, JP [1 ]
机构
[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
关键词
D O I
10.1021/ja003855k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:2931 / 2932
页数:2
相关论文
共 20 条
[1]   Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast [J].
Dove, JE ;
Schwartz, B ;
Williams, NK ;
Klinman, JP .
BIOCHEMISTRY, 2000, 39 (13) :3690-3698
[2]   Defining the arachidonic acid binding site of human 15-lipoxygenase - Molecular modeling and mutagenesis [J].
Gan, QF ;
Browner, MF ;
Sloane, DL ;
Sigal, E .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (41) :25412-25418
[4]   The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity [J].
Gillmor, SA ;
Villasenor, A ;
Fletterick, R ;
Sigal, E ;
Browner, MF .
NATURE STRUCTURAL BIOLOGY, 1997, 4 (12) :1003-1009
[5]   Lipoxygenase reaction mechanism: Demonstration that hydrogen abstraction from substrate precedes dioxygen binding during catalytic turnover [J].
Glickman, MH ;
Klinman, JP .
BIOCHEMISTRY, 1996, 35 (39) :12882-12892
[6]   Spectroscopic and functional characterization of a ligand coordination mutant of soybean lipoxygenase-1: First coordination sphere analogue of human 15-lipoxygenase [J].
Holman, TR ;
Zhou, J ;
Solomon, EI .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (48) :12564-12572
[7]   Conversion of cucumber linoleate 13-lipoxygenase to a 9-lipoxygenating species by site-directed mutagenesis [J].
Hornung, E ;
Walther, M ;
Kühn, H ;
Feussner, I .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (07) :4192-4197
[8]   Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2 [J].
Jisaka, M ;
Kim, RB ;
Boeglin, WE ;
Brash, AR .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (02) :1287-1293
[9]   The diversity of the lipoxygenase family - Many sequence data but little information on biological significance [J].
Kuhn, H ;
Thiele, BJ .
FEBS LETTERS, 1999, 449 (01) :7-11
[10]   Rapid reversed-phase high-performance liquid chromatographic determination of the regiospecificity of lipoxygenase products on linoleic acid [J].
López-Nicolás, JM ;
Pérez-Gilabert, M ;
García-Carmona, F .
JOURNAL OF CHROMATOGRAPHY A, 1999, 859 (01) :107-111