Viewpoint: Are doctors responsible for the increase in allergic diseases?

被引:12
作者
Van Bever, HP [1 ]
Shek, LPC [1 ]
Lim, DL [1 ]
Lee, BW [1 ]
机构
[1] Natl Univ Singapore, Dept Paediat, Singapore 117548, Singapore
关键词
children; allergic diseases; increase; epidemiology;
D O I
10.1111/j.1399-3038.2005.00300.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
There is no exact explanation for the increase in allergic diseases that occurred since the last two decades. An increased allergen exposure and/or a decreased bacterial load cannot explain the phenomenon completely. Other causal factors that rose at the beginning of the 1980s must be taken into consideration. Important changes at that time in our management of children were the worldwide switch from aspirin to paracetamol, the introduction of broad-spectrum antibiotics such as cephalosporins and the advice to avoid dust and pets in newborns from allergic families. General application of these new approaches, in itself or in combination, might be responsible, at least in part, for the increase of allergic diseases in children.
引用
收藏
页码:464 / 470
页数:7
相关论文
共 60 条
[51]   Childhood risk factors for atopy and the importance of early intervention [J].
Wahn, U ;
von Mutius, E .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 107 (04) :567-574
[52]   The prevalence of asthma and allergies in Singapore; data from two ISAAC surveys seven years apart [J].
Wang, XS ;
Tan, TN ;
Shek, LPC ;
Chng, SY ;
Hia, CPP ;
Ong, NBH ;
Ma, S ;
Lee, BW ;
Goh, DYT .
ARCHIVES OF DISEASE IN CHILDHOOD, 2004, 89 (05) :423-426
[53]   The early life origins of asthma and related allergic disorders [J].
Warner, JO .
ARCHIVES OF DISEASE IN CHILDHOOD, 2004, 89 (02) :97-102
[54]   Differences in fecal microflora between patients with atopic dermatitis and healthy control subjects [J].
Watanabe, S ;
Narisawa, Y ;
Arase, S ;
Okamatsu, H ;
Ikenaga, T ;
Tajiri, Y ;
Kumemura, M .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2003, 111 (03) :587-591
[55]   Phase II of the international study of asthma and allergies in childhood (ISAAC II):: rationale and methods [J].
Weiland, SK ;
Björkstén, B ;
Brunekreef, B ;
Cookson, WOC ;
von Mutius, E ;
Strachan, DP .
EUROPEAN RESPIRATORY JOURNAL, 2004, 24 (03) :406-412
[56]  
Weissman Jennifer, 2004, Semin Pediatr Infect Dis, V15, P41, DOI 10.1053/j.spid.2004.01.004
[57]  
Wickens K, 1999, CLIN EXP ALLERGY, V29, P766
[58]   Early life environmental control - Effect on symptoms, sensitization, and lung function at age 3 years [J].
Woodcock, A ;
Lowe, LA ;
Murray, CS ;
Simpson, BM ;
Pipis, SD ;
Kissen, P ;
Simpson, A ;
Custovic, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 170 (04) :433-439
[59]  
Zeiger RS, 2003, PEDIATRICS, V111, P1662
[60]   The introduction of solids in relation to asthma and eczema [J].
Zutavern, A ;
von Mutius, E ;
Harris, J ;
Mills, P ;
Moffatt, S ;
White, C ;
Cullinan, P .
ARCHIVES OF DISEASE IN CHILDHOOD, 2004, 89 (04) :303-308