Condensed and hydrolysable tannins as antioxidants influencing the health

被引：216

作者：

Koleckar, Vit ^{[1
,2
]}

Kubikova, Katerina ^{[1
]}

Rehakova, Zuzana ^{[1
]}

Kuca, Kamil ^{[2
,3
,4
]}

Jun, Daniel ^{[2
,3
]}

Jahodar, Ludek ^{[1
]}

Opletal, Lubomir ^{[1
]}

机构：

[1] Charles Univ Prague, Fac Pharm, Dept Pharmaceut Bot & Ecol, CS-50165 Hradec Kralove, Czech Republic

[2] Univ Def, Fac Mil Hlth Sci, Ctr Adv Studies, Hradec Kralove, Czech Republic

[3] Univ Def, Fac Mil Hlth Sci, Dept Toxicol, Hradec Kralove, Czech Republic

[4] J E Purkinje Univ, Fac Sci, Dept Chem, Usti Nad Labem, Czech Republic

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2008年 / 8卷 / 05期

关键词：

tannins; antioxidant; diseases; proanthocyanidins; free radicals; biological activity; phlorotannins;

D O I：

10.2174/138955708784223486

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Natural polyphenols are a wide class of secondary plant metabolites and represent an abundant antioxidant component of human diet. An important, but often neglected group of natural polyphenols, are tannins. This review offers a general description of chemistry of both hydrolysable and condensed tannins (proanthocyanidins), the mechanisms of their antioxidation action, like free radical scavenging activity, chelation of transition metals, inhibition of prooxidative enzymes and lipid peroxidation. The mechanisms of action of antibacterial, antiviral, anticarcinogenic, cardiovascular system preventing, and antiinflammatory effects as well as the absorption, metabolic fate and positive in vivo effects of tannins are enclosed.

引用

页码：436 / 447

页数：12

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