Sequence analysis of an amphioxus cosmid containing a gene homologous to members of the aldo-keto reductase gene superfamily

被引：5

作者：

Boeddrich, A ^{[1
]}

Burgtorf, C ^{[1
]}

Francis, F ^{[1
]}

Hennig, S ^{[1
]}

Panopoulou, G ^{[1
]}

Steffens, C ^{[1
]}

Borzym, K ^{[1
]}

Lehrach, H ^{[1
]}

机构：

[1] Max Planck Inst Mol Genet, D-14195 Berlin, Germany

来源：

GENE | 1999年 / 230卷 / 02期

关键词：

cosmid sequencing; exon prediction; expressed sequences;

D O I：

10.1016/S0378-1119(99)00079-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

To gain an insight into vertebrate genome evolution, we have analysed the organization of an approximately 40-kb genomic clone of an amphioxus (Branchiostoma floridae) cosmid library. Amphioxus is considered as being the last non-vertebrate relative to vertebrates. Sequencing and analysis of the above clone using three different exon prediction programs (GRAIL, GENSCAN, MZEF) have led to the identification of a gene of the aldo-keto reductase family as well as further exons that gave a significant database match to known genes. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：207 / 214

页数：8