Direct ortho-arylation of 2-arylbenzoxazoles via C-H activation

被引：48

作者：

Yang, Fan ^{[1
]}

Wu, Yangjie ^{[1
]}

Zhu, Zhiwu ^{[1
]}

Zhang, Junli ^{[1
]}

Li, Yanan ^{[1
]}

机构：

[1] Zhengzhou Univ, Dept Chem, Henan Univ, Key Lab Appl Chem,Key Lab Chem Biol & Organ Chem, Zhengzhou 450052, Peoples R China

来源：

TETRAHEDRON | 2008年 / 64卷 / 28期

基金：

中国国家自然科学基金;

关键词：

arylation; C-C coupling; palladium catalysis; C-H activation;

D O I：

10.1016/j.tet.2008.04.099

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and highly regioselective arylation of 2-arylbenzoxazoles based on C-H activation has been developed. The results represent the first examples of palladium-catalyzed direct ortho-arylation of 2-arylbenzoxazoles and also provide a facile route for the synthesis of complicated structures containing arylated benzoxazoles moieties. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：6782 / 6787

页数：6

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