Plasma homocysteine in 80-year-olds - Relationships to medical, psychological and social variables

被引：27

作者：

Jensen, E ^{[1
]}

Dehlin, O

Erfurth, EM

Hagberg, B

Samuelsson, G

Svensson, T

Hultberg, B

机构：

[1] Univ Lund Hosp, Dept Internal Med, Geriatr Sect, S-22185 Lund, Sweden

[2] Univ Lund Hosp, Dept Internal Med, Endocrinol Sect, S-22185 Lund, Sweden

[3] Gerontol Centrum, S-22220 Lund, Sweden

[4] Univ Lund Hosp, Dept Clin Chem, S-22185 Lund, Sweden

来源：

ARCHIVES OF GERONTOLOGY AND GERIATRICS | 1998年 / 26卷 / 03期

关键词：

elderly; homocysteine; symptoms; quality of life; psychology;

D O I：

10.1016/S0167-4943(98)00004-1

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Plasma homocysteine concentrations in a group of 80-year-old persons were related to symptoms and signs. Plasma homocysteine concentrations higher than 15 mu umol/l were associated with lower total life satisfaction (P < 0.01), mood (P < 0.05), zest for life (P < 0.05), lower scores for reasoning (P < 0.05), spatial ability (P < 0.05), memory recognition (P < 0.05), and subjective health (P < 0.01). In an instrument comprising of 30 symptoms, plasma homocysteine concentrations higher than 15 mu mol/l were associated with impaired concentration (P<0.05), restlessness (P<0.05), feeling cold (P<0.05), loss of weight (P < 0.05), and feeling depressed (P < 0.OI). The above data indicate that plasma homocysteine values over 15 mu mol/l could be relevant markers for clinical intervention. (C) 1998 Elsevier Science Ireland-Ltd. All rights reserved.

引用

页码：215 / 226

页数：12

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