Diffusion-weighted imaging in the assessment of neurological damage in patients with methylmalonic aciduria

被引：18

作者：

Burlina, AP

Manara, R

Calderone, M

Catuogno, S

Burlina, AB

机构：

[1] Univ Padua, Azienda Osped, Dept Pediat, I-35128 Padua, Italy

[2] Univ Padua, Azienda Osped, Dept Neurol & Psychiat Sci, I-35128 Padua, Italy

[3] Univ Padua, Azienda Osped, Dept Neuroradiol, I-35128 Padua, Italy

来源：

JOURNAL OF INHERITED METABOLIC DISEASE | 2003年 / 26卷 / 05期

关键词：

D O I：

10.1023/A:1025106909213

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Diffusion-weighted magnetic resonance imaging (DW-MRI) of the brain was performed in two patients with methylmalonic aciduria who presented signs and symptoms of neurological involvement without metabolic decompensation. Patient 1 presented acute metabolic stroke and patient 2 presented subacute encephalopathy. Brain DW-MRI confirmed very recent damage in patient 1, while the absence of brain lesions on brain DW-MRI indicates the development of more chronic damage in patient 2. Brain DW-MRI represents an additional and complementary tool in the assessment of brain damage in methylmalonic aciduria patients who develop neurological syndrome.

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收藏

页码：417 / 422

页数：6

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