Cloning of cDNA for regenectin, a humoral C-type lectin of Periplaneta americana, and expression of the regenectin gene during leg regeneration

被引:18
作者
Arai, T [1 ]
Kawasaki, K [1 ]
Kubo, T [1 ]
Natori, S [1 ]
机构
[1] Univ Tokyo, Fac Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
关键词
cockroach; c-type lectin; cDNA cloning; regenectin; regeneration;
D O I
10.1016/S0965-1748(98)00087-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We isolated cDNA for regenectin, a C-type lectin of the American cockroach (Periplaneta americana), and analysed expression of the regenectin gene in the regenerating legs. Regenectin was found to be a member of the Periplaneta lectin-related protein family. We found that the regenectin gene was expressed specifically in the epidermal cells of the newly formed regenerating legs. Together with our previous results, these results suggest that regenectin is synthesized by epidermal cells, secreted into the regenerating leg saccule, and assembles around myoblasts to form leg muscle fibers in situ. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:987 / 994
页数:8
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