Basilar artery occlusion

被引:487
作者
Mattle, Heinrich P. [1 ]
Arnold, Marcel [1 ]
Lindsberg, Perttu J. [3 ,4 ]
Schonewille, Wouter J. [5 ,6 ]
Schroth, Gerhard [2 ]
机构
[1] Univ Bern, Inselspital, Dept Neurol, CH-3010 Bern, Switzerland
[2] Univ Bern, Inselspital, Dept Diagnost & Intervent Neuroradiol, CH-3010 Bern, Switzerland
[3] Univ Helsinki, Cent Hosp, Dept Neurol, Helsinki, Finland
[4] Univ Helsinki, Biomedicum Helsinki, Res Programs Unit, Helsinki, Finland
[5] St Antonius Hosp, Dept Neurol, Nieuwegein, Netherlands
[6] Univ Med Ctr Utrecht, Utrecht, Netherlands
关键词
ACUTE ISCHEMIC-STROKE; LOCKED-IN-SYNDROME; ACUTE VERTEBROBASILAR OCCLUSION; CEREBRAL-BLOOD-FLOW; MECHANICAL THROMBECTOMY; INTERNATIONAL-COOPERATION; INTRAVENOUS THROMBOLYSIS; LOCAL FIBRINOLYSIS; EVOKED-POTENTIALS; BRAIN-STEM;
D O I
10.1016/S1474-4422(11)70229-0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or Mill, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.
引用
收藏
页码:1002 / 1014
页数:13
相关论文
共 108 条
  • [1] DISSECTING ANEURYSMS OF THE BASILAR ARTERY IN 2 PATIENTS
    ALEXANDER, CB
    BURGER, PC
    GOREE, JA
    [J]. STROKE, 1979, 10 (03) : 294 - 299
  • [2] ARTERIAL PATHOLOGY IN CEREBELLAR INFARCTION
    AMARENCO, P
    HAUW, JJ
    GAUTIER, JC
    [J]. STROKE, 1990, 21 (09) : 1299 - 1305
  • [3] End-of-life decision-making in individuals with Locked-in syndrome in the acute period after brainstem stroke
    Anderson, J. F. I.
    Augoustakis, L. V.
    Holmes, R. J.
    Chambers, B. R.
    [J]. INTERNAL MEDICINE JOURNAL, 2010, 40 (01) : 61 - 65
  • [4] [Anonymous], J NEUROIMAGING
  • [5] [Anonymous], CEREBROVASC IN PRESS
  • [6] [Anonymous], REV NEUROL PARIS
  • [7] [Anonymous], TRIAL INF BAS ART IN
  • [8] BASILAR ARTERY-OCCLUSION - CLINICAL AND RADIOLOGICAL CORRELATION
    ARCHER, CR
    HORENSTEIN, S
    [J]. STROKE, 1977, 8 (03) : 383 - 390
  • [9] Clinical and radiological predictors of recanalisation and outcome of 40 patients with acute basilar artery occlusion treated with intra-arterial thrombolysis
    Arnold, M
    Nedeltchev, K
    Schroth, G
    Baumgartner, RW
    Remonda, L
    Loher, TJ
    Stepper, F
    Sturzenegger, M
    Schuknecht, B
    Mattle, HP
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2004, 75 (06) : 857 - 862
  • [10] Acute Basilar Artery Occlusion in the Basilar Artery International Cooperation Study Does Gender Matter?
    Arnold, Marcel
    Fischer, Urs
    Compter, Annette
    Gralla, Jan
    Findling, Oliver
    Mattle, Heinrich P.
    Kappelle, L. Jaap
    Tanne, David
    Algra, Ale
    Schonewille, Wouter J.
    [J]. STROKE, 2010, 41 (11) : 2693 - 2696