Basilar artery occlusion

被引:487
作者
Mattle, Heinrich P. [1 ]
Arnold, Marcel [1 ]
Lindsberg, Perttu J. [3 ,4 ]
Schonewille, Wouter J. [5 ,6 ]
Schroth, Gerhard [2 ]
机构
[1] Univ Bern, Inselspital, Dept Neurol, CH-3010 Bern, Switzerland
[2] Univ Bern, Inselspital, Dept Diagnost & Intervent Neuroradiol, CH-3010 Bern, Switzerland
[3] Univ Helsinki, Cent Hosp, Dept Neurol, Helsinki, Finland
[4] Univ Helsinki, Biomedicum Helsinki, Res Programs Unit, Helsinki, Finland
[5] St Antonius Hosp, Dept Neurol, Nieuwegein, Netherlands
[6] Univ Med Ctr Utrecht, Utrecht, Netherlands
关键词
ACUTE ISCHEMIC-STROKE; LOCKED-IN-SYNDROME; ACUTE VERTEBROBASILAR OCCLUSION; CEREBRAL-BLOOD-FLOW; MECHANICAL THROMBECTOMY; INTERNATIONAL-COOPERATION; INTRAVENOUS THROMBOLYSIS; LOCAL FIBRINOLYSIS; EVOKED-POTENTIALS; BRAIN-STEM;
D O I
10.1016/S1474-4422(11)70229-0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or Mill, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.
引用
收藏
页码:1002 / 1014
页数:13
相关论文
共 108 条
  • [61] Therapy of basilar artery occlusion - A systematic analysis comparing intra-arterial and intravenous thrombolysis
    Lindsberg, PJ
    Mattle, HP
    [J]. STROKE, 2006, 37 (03) : 922 - 928
  • [62] Long-term outcome after intravenous thrombolysis of basilar artery occlusion
    Lindsberg, PJ
    Soinne, L
    Tatlisumak, T
    Roine, RO
    Kallela, M
    Häppölä, O
    Kaste, M
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (15): : 1862 - 1866
  • [63] Vertebrobasilar dilatative arteriopathy (dolichoectasia)
    Lou, Min
    Caplan, Louis R.
    [J]. YEAR IN NEUROLOGY 2, 2010, 1184 : 121 - 133
  • [64] Life can be worth living in locked-in syndrome
    Lule, D.
    Zickler, C.
    Haecker, S.
    Bruno, M. A.
    Demertzi, A.
    Pellas, F.
    Laureys, S.
    Kuebler, A.
    [J]. COMA SCIENCE: CLINICAL AND ETHICAL IMPLICATIONS, 2009, 177 : 339 - 351
  • [65] Lutsep Helmi L, 2008, J Stroke Cerebrovasc Dis, V17, P55, DOI 10.1016/j.jstrokecerebrovasdis.2007.11.003
  • [66] Results of a multicentre, randomised controlled trial of intra-arterial urokinase in the treatment of acute posterior circulation ischaemic stroke
    Macleod, MR
    Davis, SM
    Mitchell, PJ
    Gerraty, RP
    Fitt, G
    Hankey, GJ
    Stewart-Wynne, EG
    Rosen, D
    McNeil, JJ
    Bladin, CF
    Chambers, BR
    Herkes, GK
    Young, D
    Donnan, GA
    [J]. CEREBROVASCULAR DISEASES, 2005, 20 (01) : 12 - 17
  • [67] Complex visual hallucinations Clinical and neurobiological insights
    Manford, M
    Andermann, F
    [J]. BRAIN, 1998, 121 : 1819 - 1840
  • [68] THE SURGICAL ANATOMY OF THE PERFORATING BRANCHES OF THE BASILAR ARTERY
    MARINKOVIC, SV
    GIBO, H
    [J]. NEUROSURGERY, 1993, 33 (01) : 80 - 87
  • [69] THE ROSTRAL BASILAR ARTERY SYNDROME - DIAGNOSIS, ETIOLOGY, PROGNOSIS
    MEHLER, MF
    [J]. NEUROLOGY, 1989, 39 (01) : 9 - 16
  • [70] Initial experience with a self-expanding retrievable stent for recanalization of large vessel occlusions in acute ischemic stroke
    Menon, Bijoy K.
    Kochar, Puneet
    Ah-Seng, Andrew
    Almekhlafi, Mohammed A.
    Modi, Jayesh
    Wong, John H.
    Hudon, Mark E.
    Morrish, Will
    Demchuk, Andrew M.
    Goyal, Mayank
    [J]. NEURORADIOLOGY, 2012, 54 (02) : 147 - 154