Second messenger systems and mood disorders

被引：31

作者：

Warsh, JJ

Li, PP

机构：

[1] UNIV TORONTO,DEPT PSYCHIAT,TORONTO,ON,CANADA

[2] UNIV TORONTO,DEPT PHARMACOL,TORONTO,ON,CANADA

[3] UNIV TORONTO,INST MED SCI,TORONTO,ON,CANADA

来源：

CURRENT OPINION IN PSYCHIATRY | 1996年 / 9卷 / 01期

关键词：

D O I：

10.1097/00001504-199601000-00005

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Advances have been made in several areas of second messenger and signal transduction research in mood disorders. Evidence from postmortem brain and clinical studies which implicates disturbances in signal-transducing guanine nucleotide binding proteins in bipolar disorder is discussed as well as results of studies suggesting that mood stabilizing agents, particularly lithium, act on intracellular signaling targets. Findings supporting disturbances in inositol phospholipid and intracellular calcium signaling systems in affective disorders are also described.

引用

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页码：23 / 29

页数：7

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