Immune privilege or inflammation? Insights into the Fas ligand enigma

被引：132

作者：

O'Connell, J ^{[1
]}

Houston, A

Bennett, MW

O'Sullivan, G

Shanahan, F

机构：

[1] Natl Univ Ireland, Univ Hosp, Dept Med, Cork, Ireland

[2] Natl Univ Ireland, Mercy Hosp, Dept Surg, Cork, Ireland

来源：

NATURE MEDICINE | 2001年 / 7卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1038/85395

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fas ligand (FasL) has become an enigmatic molecule: some evidence indicates that it contributes to immune privilege in tissues and tumors, whereas other data demonstrates that FasL can elicit inflammation. New findings may begin to reconcile the paradoxical effects of FasL.

引用

页码：271 / 274

页数：4

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