Immune privilege or inflammation? Insights into the Fas ligand enigma

被引:132
作者
O'Connell, J [1 ]
Houston, A
Bennett, MW
O'Sullivan, G
Shanahan, F
机构
[1] Natl Univ Ireland, Univ Hosp, Dept Med, Cork, Ireland
[2] Natl Univ Ireland, Mercy Hosp, Dept Surg, Cork, Ireland
基金
英国惠康基金;
关键词
D O I
10.1038/85395
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Fas ligand (FasL) has become an enigmatic molecule: some evidence indicates that it contributes to immune privilege in tissues and tumors, whereas other data demonstrates that FasL can elicit inflammation. New findings may begin to reconcile the paradoxical effects of FasL.
引用
收藏
页码:271 / 274
页数:4
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