Synthesis of asymmetric septi-(p-phenylene)s

被引：17

作者：

Ghebremariam, B ^{[1
]}

Matile, S ^{[1
]}

机构：

[1] Georgetown Univ, Dept Chem, Washington, DC 20057 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 30期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(98)01041-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this Letter, we describe the synthesis of two amphiphilic septi(p-phenylene)s, One terminus of each rigid-rod scaffold is linked through a spacer to a hydrophilic IDA-subunit, the two benzenes at the other terminus carry hydrophobic substituents of different size. These synthetic receptor models are expected to mimic biological processes that occur at cell membranes. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5335 / 5338

页数：4

共 12 条

[1] Alberts B., 1994, MOL BIOL CELL
[2] Molecular recognition-controlled membrane disruption by a bis(crown ether) bola-amphiphile
Fyles, TM
Zeng, BQ
[J]. CHEMICAL COMMUNICATIONS, 1996, (19) : 2295 - 2296
[3] HEITZ W, 1966, MAKROMOLEKUL CHEM, V98, P29
[4] TOTAL SYNTHESIS OF DL-ALNUSENONE
IRELAND, RE
WELCH, SC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (24) : 7232 - &
[5] Fluorescence signaling of ligand binding and assembly in metal-chelating lipid membranes
Maloney, KM
Shnek, DR
Sasaki, DY
Arnold, FH
[J]. CHEMISTRY & BIOLOGY, 1996, 3 (03): : 185 - 192
[6] PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS OF ORGANOBORON COMPOUNDS
MIYAURA, N
SUZUKI, A
[J]. CHEMICAL REVIEWS, 1995, 95 (07) : 2457 - 2483
[7] Side-chain hydrophobicity controls the activity of proton channel forming rigid rod-shaped polyols
Ni, CY
Matile, S
[J]. CHEMICAL COMMUNICATIONS, 1998, (07) : 755 - 756
[8] SYNTHESIS OF PEPTIDES CONTAINING UNNATURAL, METAL-LIGATING RESIDUES - AMINODIACETIC ACID AS A PEPTIDE SIDE-CHAIN
RUAN, FQ
CHEN, YQ
ITOH, K
SASAKI, T
HOPKINS, PB
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (14) : 4347 - 4354
[9] Toward biomimetic ion channels formed by rigid-rod molecules: Length-dependent ion-transport activity of substituted oligo(p-phenylene)s
Sakai, N
Brennan, KC
Weiss, LA
Matile, S
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (37) : 8726 - 8727
[10] Stereodependent fusion and fission of vesicles: Calcium binding of synthetic gemini phospholipids containing two phosphate groups
Sommerdijk, NAJM
Hoeks, THL
Synak, M
Feiters, MC
Nolte, RJM
Zwanenburg, B
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (19) : 4338 - 4344

← 1 2 →