Community genomics in microbial ecology and evolution

被引:128
作者
Allen, EE
Banfield, JF [1 ]
机构
[1] Univ Calif Berkeley, Dept Environm Sci Policy & Management, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Dept Earth & Planetary Sci, Berkeley, CA 94720 USA
关键词
D O I
10.1038/nrmicro1157
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
It is Possible to reconstruct near-complete, and possibly complete, genomes of the dominant members of microbial communities from DNA that is extracted directly from the environment. Genome sequences from environmental samples capture the aggregate characteristics of the strain population from which they were derived. Comparison of the sequence data within and among natural populations can reveal the evolutionary processes that lead to genome diversification and speciation. Community genomic datasets can also enable subsequent gene expression and proteomic studies to determine how resources are invested and functions are distributed among community members. Ultimately, genomics can reveal how individual species and strains contribute to the net activity of the community.
引用
收藏
页码:489 / 498
页数:10
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