Dissemination of New Delhi metallo-ß-lactamase-1-producing Acinetobacter baumannii in Europe

被引:106
作者
Bonnin, R. A. [1 ,2 ]
Poirel, L. [1 ,2 ]
Naas, T. [1 ,2 ]
Pirs, M. [3 ]
Seme, K. [3 ]
Schrenzel, J. [4 ,5 ]
Nordmann, P. [1 ,2 ]
机构
[1] Hop Bicetre, AP HP, Fac Med, Serv Bacteriol Virol,INSERM Emerging Resistance A, K Bicetre, France
[2] Univ Paris 11, K Bicetre, France
[3] Univ Ljubljana, Fac Med, Inst Microbiol & Immunol, Ljubljana, Slovenia
[4] Univ Hosp Geneva, Bacteriol Lab, Geneva, Switzerland
[5] Univ Hosp Geneva, Genom Res Lab, Geneva, Switzerland
关键词
Carbapenemase; Gram-negative rods; New Delhi metallo-ss-lactamase; Tn125; ANTIBIOTIC-RESISTANCE; NDM-2; CARBAPENEMASE; MULTIPLEX PCR; BLA(NDM-1); EMERGENCE; SEQUENCE; DNA; BLA(OXA-23); GENES;
D O I
10.1111/j.1469-0691.2012.03928.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Clin Microbiol Infect 2012; 18: E362E365 Abstract Multidrug-resistant and New Delhi metallo-beta-lactamase 1 (NDM-1) -producing Acinetobacter baumannii are increasingly reported. A collection of five NDM-1-positive A. baumannii isolates recovered in four European countries were analysed. Genotyping was performed by pulsed-field gel electrophoresis, multiplex PCR sequence typing, Diversilab and multilocus sequence typing. Three distinct sequence types were identified. All isolates harboured a chromosomally located blaNDM-1 gene within a Tn125-like transposon. One isolate co-expressed another unrelated carbapenemase OXA-23. This report constitutes the first epidemiological study of NDM-1-producing A. baumannii from four countries.
引用
收藏
页码:E362 / E365
页数:4
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