Polymorph control:: past, present and future

被引：269

作者：

Llinas, Antonio ^{[1
]}

Goodman, Jonathan M. ^{[2
]}

机构：

[1] Univ Cambridge, Pfizer Inst Pharmaceut Mat Sci, Dept Chem, Cambridge CB2 1EW, England

[2] Univ Cambridge, Unilever Ctr Mol Informat, Dept Chem, Cambridge CB2 1EW, England

来源：

DRUG DISCOVERY TODAY | 2008年 / 13卷 / 5-6期

关键词：

D O I：

10.1016/j.drudis.2007.11.006

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The appearance and disappearance of polymorphs is no longer a mysterious and inexplicable process. Although methods for polymorph control are still imperfect, there is a large armoury of methods that can be used to tackle this, important and challenging problem. We survey the methods and their successes over the last few years.

引用

页码：198 / 210

页数：13

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